Assessing Lung Cancer Absolute Risk Trajectory based on a Polygenic Risk Model

Lung cancer is the leading cause of cancer death globally. An improved risk stratification strategy can increase efficiency of low-dose computed tomography (LDCT) screening. Here we assessed whether individual’s genetic background has clinical utility for risk stratification in the context of LDCT s...

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Publicado en:Cancer Res
Main Authors: Hung, Rayjean J., Warkentin, Matthew T., Brhane, Yonathan, Chatterjee, Nilanjan, Christiani, David C., Landi, Maria Teresa, Caporaso, Neil E., Liu, Geoffrey, Johansson, Mattias, Albanes, Demetrius, Le Marchand, Loic, Tardon, Adonina, Rennert, Gad, Bojesen, Stig E., Chen, Chu, Field, John K., Kiemeney, Lambertus A., Lazarus, Philip, Zienolddiny, Shanbeth, Lam, Stephen, Andrew, Angeline S., Arnold, Susanne M., Aldrich, Melinda C., Bickeböller, Heike, Risch, Angela, Schabath, Matthew B., McKay, James D., Brennan, Paul, Amos, Christopher I.
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969419/
https://ncbi.nlm.nih.gov/pubmed/33472890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-20-1237
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