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Sexual dimorphism in the nociceptive effects of hyaluronan

Intradermal administration of low molecular weight hyaluronan (LMWH) in the hindpaw induced dose-dependent (0.1, 1, or 10 μg) mechanical hyperalgesia, of similar magnitude in male and female rats. However, the duration of LMWH hyperalgesia was greater in females. This sexual dimorphism was eliminate...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Bonet, Ivan J. M., Green, Paul G., Levine, Jon D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969372/
https://ncbi.nlm.nih.gov/pubmed/33065736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000002116
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