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Mutations in genes affecting DNA methylation enhances responses to decitabine in patients with myelodysplastic syndrome
BACKGROUND/AIMS: In this study, we tested whether mutations in the methylation pathway genes ten-eleven-translocation 2 (TET2) and DNA methyltransferase gene 3A (DNMT3A) improve the responses of patients with myelodysplastic syndrome (MDS) to decitabine. METHODS: We retrospectively sequenced the TET...
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| Veröffentlicht in: | Korean J Intern Med |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Korean Association of Internal Medicine
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7969079/ https://ncbi.nlm.nih.gov/pubmed/33086776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3904/kjim.2019.385 |
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