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Tandem RNA binding sites induce self-association of the stress granule marker protein TIA-1
TIA-1 is an RNA-binding protein that sequesters target RNA into stress granules under conditions of cellular stress. Promotion of stress granule formation by TIA-1 depends upon self-association of its prion-like domain that facilitates liquid-liquid phase separation and is thought to be enhanced via...
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| 發表在: | Nucleic Acids Res |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7969032/ https://ncbi.nlm.nih.gov/pubmed/33621982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab080 |
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