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PEGylation enables subcutaneously administered nanoparticles to induce antigen-specific immune tolerance

The development of nanomaterials to induce antigen-specific immune tolerance has shown promise for treating autoimmune diseases. While PEGylation has been widely used to reduce host immune responses to nanomaterials, its tolerogenic potential has not been reported. Here, we report for the first time...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Li, Peter Y., Bearoff, Frank, Zhu, Pu, Fan, Zhiyuan, Zhu, Yucheng, Fan, Mingyue, Cort, Laura, Kambayashi, Taku, Blankenhorn, Elizabeth P., Cheng, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7968989/
https://ncbi.nlm.nih.gov/pubmed/33450320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2021.01.013
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