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Basis of specificity for a conserved and promiscuous chromatin remodeling protein
Eukaryotic genomes are organized dynamically through the repositioning of nucleosomes. Isw2 is an enzyme that has been previously defined as a genome-wide, nonspecific nucleosome spacing factor. Here, we show that Isw2 instead acts as an obligately targeted nucleosome remodeler in vivo through physi...
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| 出版年: | eLife |
|---|---|
| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
eLife Sciences Publications, Ltd
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7968928/ https://ncbi.nlm.nih.gov/pubmed/33576335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64061 |
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