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Theory of Allosteric Regulation in Hsp70 Molecular Chaperones

Heat-shock proteins of 70 kDa (Hsp70s) are ubiquitous molecular chaperones that function in protein folding as well as other vital cellular processes. They bind and hydrolyze ATP in a nucleotide-binding domain (NBD) to control the binding and release of client polypeptides in a substrate-binding dom...

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Détails bibliographiques
Publié dans:QRB Discov
Auteur principal: Hendrickson, Wayne A.
Format: Artigo
Langue:Inglês
Publié: Cambridge University Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7968864/
https://ncbi.nlm.nih.gov/pubmed/33738455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/qrd.2020.10
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