Combined genomic and proteomic approaches reveal DNA binding sites and interaction partners of TBX2 in the developing lung

BACKGROUND: Tbx2 encodes a transcriptional repressor implicated in the development of numerous organs in mouse. During lung development TBX2 maintains the proliferation of mesenchymal progenitors, and hence, epithelial proliferation and branching morphogenesis. The pro-proliferative function was tra...

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Udgivet i:Respir Res
Main Authors: Lüdtke, Timo H., Wojahn, Irina, Kleppa, Marc-Jens, Schierstaedt, Jasper, Christoffels, Vincent M., Künzler, Patrick, Kispert, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7968368/
https://ncbi.nlm.nih.gov/pubmed/33731112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01679-y
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