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Pathway size matters: the influence of pathway granularity on over-representation (enrichment analysis) statistics
BACKGROUND: Enrichment or over-representation analysis is a common method used in bioinformatics studies of transcriptomics, metabolomics, and microbiome datasets. The key idea behind enrichment analysis is: given a set of significantly expressed genes (or metabolites), use that set to infer a small...
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| Udgivet i: | BMC Genomics |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7967953/ https://ncbi.nlm.nih.gov/pubmed/33726670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-021-07502-8 |
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