Effects of Nicotine Metabolic Rate on Withdrawal Symptoms and Response to Cigarette Smoking After Abstinence

This study investigated the influence of the rate of nicotine metabolism, as indicated by the nicotine metabolite ratio (NMR), on tobacco dependence. We stratified 136 smokers on the basis of saliva NMR as fast (n = 65) and slow (n = 71) metabolizers. Two “loading cigarettes” were smoked after overn...

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Bibliographic Details
Published in:Clin Pharmacol Ther
Main Authors: Liakoni, Evangelia, Edwards, Kathryn C., Helen, Gideon St., Nardone, Natalie, Dempsey, Delia A., Tyndale, Rachel F., Benowitz, Neal L.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967935/
https://ncbi.nlm.nih.gov/pubmed/30242831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1238
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