FTLD-TDP With and Without GRN Mutations Cause Different Patterns of CA1 Pathology

Heterozygous loss-of-function mutations in the GRN gene lead to progranulin (PGRN) haploinsufficiency and cause frontotemporal lobar degeneration with TDP-43 pathology type A (FTLD-TDP type A). PGRN is a highly conserved, secreted glycoprotein and functions in the central nervous system as a key mod...

全面介紹

Na minha lista:
書目詳細資料
發表在:J Neuropathol Exp Neurol
Main Authors: Mao, Qinwen, Zheng, Xiaojing, Gefen, Tamar, Rogalski, Emily, Spencer, Callen L, Rademakers, Rosa, Fought, Angela J, Kohler, Missia, Weintraub, Sandra, Xia, Haibin, Mesulam, Marek-Marsel, Bigio, Eileen H
格式: Artigo
語言:Inglês
出版: Oxford University Press 2019
主題:
Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967835/
https://ncbi.nlm.nih.gov/pubmed/31361008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlz059
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍