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The Leukotriene Receptor Antagonist Montelukast Attenuates Neuroinflammation and Affects Cognition in Transgenic 5xFAD Mice

Alzheimer’s disease (AD) is the most common form of dementia. In particular, neuroinflammation, mediated by microglia cells but also through CD8+ T-cells, actively contributes to disease pathology. Leukotrienes are involved in neuroinflammation and in the pathological hallmarks of AD. In consequence...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Michael, Johanna, Zirknitzer, Julia, Unger, Michael Stefan, Poupardin, Rodolphe, Rieß, Tanja, Paiement, Nadine, Zerbe, Horst, Hutter-Paier, Birgit, Reitsamer, Herbert, Aigner, Ludwig
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967180/
https://ncbi.nlm.nih.gov/pubmed/33803482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052782
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