PADI2‐Catalyzed MEK1 Citrullination Activates ERK1/2 and Promotes IGF2BP1‐Mediated SOX2 mRNA Stability in Endometrial Cancer

Peptidylarginine deiminase II (PADI2) converts positively charged arginine residues to neutrally charged citrulline, and this activity has been associated with the onset and progression of multiple cancers. However, a role for PADI2 in endometrial cancer (EC) has not been previously explored. This s...

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Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Xue, Teng, Liu, Xiaoqiu, Zhang, Mei, E, Qiukai, Liu, Shuting, Zou, Maosheng, Li, Ying, Ma, Zhinan, Han, Yun, Thompson, Paul, Zhang, Xuesen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7967072/
https://ncbi.nlm.nih.gov/pubmed/33747724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202002831
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