Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies

Neutralizing monoclonal antibodies (nAbs) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represent promising candidates for clinical intervention against coronavirus disease 2019 (COVID-19). We isolated a large number of nAbs from SARS-CoV-2-infected individuals capable of disruptin...

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Publicado no:Cell Res
Main Authors: Yan, Renhong, Wang, Ruoke, Ju, Bin, Yu, Jinfang, Zhang, Yuanyuan, Liu, Nan, Wang, Jia, Zhang, Qi, Chen, Peng, Zhou, Bing, Li, Yaning, Shen, Yaping, Zhang, Shuyuan, Tian, Long, Guo, Yingying, Xia, Lu, Zhong, Xinyue, Cheng, Lin, Ge, Xiangyang, Zhao, Juanjuan, Wang, Hong-Wei, Wang, Xinquan, Zhang, Zheng, Zhang, Linqi, Zhou, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966918/
https://ncbi.nlm.nih.gov/pubmed/33731853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-021-00487-9
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