Regulation of hepatic circadian metabolism by the E3 ubiquitin ligase HRD1-controlled CREBH/PPARα transcriptional program

OBJECTIVE: The endoplasmic reticulum (ER)-resident E3 ligase HRD1 and its co-activator Sel1L are major components of ER-associated degradation (ERAD) machinery. Here, we investigated the molecular mechanism and functional significance underlying the circadian regulation of HRD1/Sel1L-mediated protei...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Kim, Hyunbae, Wei, Juncheng, Song, Zhenfeng, Mottillo, Emilio, Samavati, Lobelia, Zhang, Ren, Li, Li, Chen, Xuequn, Jena, Bhanu P., Lin, Jiandie D., Fang, Deyu, Zhang, Kezhong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966871/
https://ncbi.nlm.nih.gov/pubmed/33592335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101192
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados