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CD73 facilitates EMT progression and promotes lung metastases in triple-negative breast cancer

CD73 is a cell surface ecto-5′-nucleotidase, which converts extracellular adenosine monophosphate to adenosine. High tumor CD73 expression is associated with poor outcome among triple-negative breast cancer (TNBC) patients. Here we investigated the mechanisms by which CD73 might contribute to TNBC p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Petruk, Nataliia, Tuominen, Sanni, Åkerfelt, Malin, Mattsson, Jesse, Sandholm, Jouko, Nees, Matthias, Yegutkin, Gennady G., Jukkola, Arja, Tuomela, Johanna, Selander, Katri S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966763/
https://ncbi.nlm.nih.gov/pubmed/33727591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85379-z
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