Toll-like receptor 9 expression is associated with breast cancer sensitivity to the growth inhibitory effects of bisphosphonates in vitro and in vivo

Bisphosphonates are standard treatments for bone metastases. When given in the adjuvant setting, they reduce breast cancer mortality and recurrence in bone but only among post-menopausal patients. Optimal drug use would require biomarker-based patient selection. Such biomarkers are not yet in clinic...

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Udgivet i:Oncotarget
Main Authors: Sandholm, Jouko, Lehtimäki, Jaakko, Ishizu, Tamiko, Velu, Sadanandan E., Clark, Jeremy, Härkönen, Pirkko, Jukkola-Vuorinen, Arja, Schrey, Aleksi, Harris, Kevin W., Tuomela, Johanna M., Selander, Katri S.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349995/
https://ncbi.nlm.nih.gov/pubmed/27888633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13570
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