Engineering of Aeromonas caviae Polyhydroxyalkanoate Synthase Through Site-Directed Mutagenesis for Enhanced Polymerization of the 3-Hydroxyhexanoate Unit

Polyhydroxyalkanoate (PHA) synthase is an enzyme that polymerizes the acyl group of hydroxyacyl-coenzyme A (CoA) substrates. Aeromonas caviae PHA synthase (PhaC(Ac)) is an important biocatalyst for the synthesis of a useful PHA copolymer, poly[(R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate] [P(3HB-...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Harada, Ken, Kobayashi, Shingo, Oshima, Kanji, Yoshida, Shinichi, Tsuge, Takeharu, Sato, Shunsuke
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966705/
https://ncbi.nlm.nih.gov/pubmed/33748082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.627082
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