Targeting the Kaposi’s sarcoma-associated herpesvirus genome with the CRISPR-Cas9 platform in latently infected cells

BACKGROUND: Kaposi’s sarcoma-associated herpesvirus (KSHV) is a transforming gammaherpesvirus. Like other herpesviruses, KSHV infection is for life long and there is no treatment that can cure patients from the virus. In addition, there is an urgent need to target viral genes to study their role dur...

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Veröffentlicht in:Virol J
Hauptverfasser: Haddad, Coral Orel, Kalt, Inna, Shovman, Yehuda, Xia, Lei, Schlesinger, Yehuda, Sarid, Ronit, Parnas, Oren
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966637/
https://ncbi.nlm.nih.gov/pubmed/33731154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-021-01527-x
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