Targeting the Kaposi’s sarcoma-associated herpesvirus genome with the CRISPR-Cas9 platform in latently infected cells

BACKGROUND: Kaposi’s sarcoma-associated herpesvirus (KSHV) is a transforming gammaherpesvirus. Like other herpesviruses, KSHV infection is for life long and there is no treatment that can cure patients from the virus. In addition, there is an urgent need to target viral genes to study their role dur...

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Bibliografiske detaljer
Udgivet i:Virol J
Main Authors: Haddad, Coral Orel, Kalt, Inna, Shovman, Yehuda, Xia, Lei, Schlesinger, Yehuda, Sarid, Ronit, Parnas, Oren
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966637/
https://ncbi.nlm.nih.gov/pubmed/33731154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-021-01527-x
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