Charge-Transfer Complex of Linifanib with 2,3-dichloro-3,5-dicyano-1,4-benzoquinone: Synthesis, Spectroscopic Characterization, Computational Molecular Modelling and Application in the Development of Novel 96-microwell Spectrophotometric Assay

BACKGROUND: Linifanib (LFB) is a multi‐targeted receptor tyrosine kinase inhibitor used in the treatment of hepatocellular carcinoma and other types of cancer. The charge-transfer (CT) interaction of LFB is important in studying its receptor binding mechanisms and useful in the development of a reli...

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Bibliografski detalji
Izdano u:Drug Des Devel Ther
Glavni autori: Darwish, Ibrahim A, Khalil, Nasr Y, Alsaif, Nawaf A, Herqash, Rashed N, Sayed, Ahmed Y A, Abdel-Rahman, Hamdy M
Format: Artigo
Jezik:Inglês
Izdano: Dove 2021
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966300/
https://ncbi.nlm.nih.gov/pubmed/33737805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S296502
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