Charge–transfer reaction of 2,3-dichloro-1,4-naphthoquinone with crizotinib: Spectrophotometric study, computational molecular modeling and use in development of microwell assay for crizotinib

The reaction of 2,3-dichloro-1,4-naphthoquinone (DCNQ) with crizotinib (CZT; a novel drug used for treatment of non-small cell lung cancer) was investigated in different solvents of varying dielectric constants and polarity indexes. The reaction produced a red-colored product. Spectrophotometric inv...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Saudi Pharm J
Hlavní autoři: Alzoman, Nourah Z., Alshehri, Jamilah M., Darwish, Ibrahim A., Khalil, Nasr Y., Abdel-Rahman, Hamdy M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310957/
https://ncbi.nlm.nih.gov/pubmed/25685046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2014.06.003
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky