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Combating deleterious phase transitions in neurodegenerative disease

Protein aggregation is a hallmark of neurodegenerative diseases. However, the mechanism that induces pathogenic aggregation is not well understood. Recently, it has emerged that several of the pathological proteins found in an aggregated or mislocalized state in neurodegenerative diseases are also a...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Cell Res
Main Authors: Darling, April L., Shorter, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7965345/
https://ncbi.nlm.nih.gov/pubmed/33549703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2021.118984
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