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Re-evaluation of the mechanism of cytotoxicity of dialkylated lariat ether compounds

The cytotoxicity of dialkylated lariat ethers has been previously attributed to their ionophoric properties. Herein, we provide evidence that these effects are due to loss of membrane integrity rather than ion transport, a finding with important implications for the future design of synthetic ionoph...

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Bibliografiska uppgifter
I publikationen:RSC Adv
Huvudupphovsmän: Carrasquel-Ursulaez, Willy, Reeves, Ryan D., Dehghany, Mahzad, Jones, Corey, Schomaker, Jennifer M., Chanda, Baron
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Royal Society of Chemistry 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963367/
https://ncbi.nlm.nih.gov/pubmed/33732448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0ra08494h
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