Chidamide Combined With Doxorubicin Induced p53-Driven Cell Cycle Arrest and Cell Apoptosis Reverse Multidrug Resistance of Breast Cancer

The multidrug-resistant (MDR) phenotype is usually accompanied by an abnormal expression of histone deacetylase (HDAC). Given that HDAC is vital in chromatin remodeling and epigenetics, inhibiting the role of HDAC has become an important approach for tumor treatment. However, the effect of HDAC inhi...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Cao, Lixia, Zhao, Shaorong, Yang, Qianxi, Shi, Zhendong, Liu, Jingjing, Pan, Teng, Zhou, Dongdong, Zhang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962870/
https://ncbi.nlm.nih.gov/pubmed/33738256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.614458
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