Modulated electro‐hyperthermia induced p53 driven apoptosis and cell cycle arrest additively support doxorubicin chemotherapy of colorectal cancer in vitro

OBJECTIVE: Modulated electro‐hyperthermia (mEHT), a noninvasive complementary treatment of human chemo‐ and radiotherapy, can generate selective ~42°C heat in cancer due to elevated glycolysis (Warburg‐effect) and electric conductivity in malignant tissues. Here we tested the molecular background of...

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Bibliographic Details
Published in:Cancer Med
Main Authors: Vancsik, Tamas, Forika, Gertrud, Balogh, Andrea, Kiss, Eva, Krenacs, Tibor
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
Cancer Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675742/
https://ncbi.nlm.nih.gov/pubmed/31183995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2330
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