Polymorphisms in the Gene Encoding Caspase 8 May Predict the Response to First-Line Platinum-Based Chemotherapy in Locally Advanced or Advanced Non-Small-Cell Lung Cancer

Caspase 8 is a protein involved in the process of cell apoptosis, which may affect the efficacy of anti-cancer treatment. The aim of our study was to determine the impact of polymorphisms in the CASP-8 gene encoding caspase 8 on the prognosis in non-small-cell lung cancer (NSCLC). The study involved...

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Veröffentlicht in:J Clin Med
Hauptverfasser: Szczyrek, Michał, Mlak, Radosław, Szudy-Szczyrek, Aneta, Kędziora, Karolina, Małecka-Massalska, Teresa, Krawczyk, Paweł, Milanowski, Janusz
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962636/
https://ncbi.nlm.nih.gov/pubmed/33800294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10051126
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