Polymorphisms in the promoter region of the CRBN gene as a predictive factor for the first-line CTD therapy in multiple myeloma patients

Cereblon is a primary molecular target for immunomodulatory drugs. The aim of this study was to evaluate the influence of selected clinical and molecular factors including single nucleotide polymorphisms (SNPs) in CRBN gene on the efficacy of first line CTD (cyclophosphamide, thalidomide, dexamethas...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Szudy-Szczyrek, Aneta, Mlak, Radosław, Szczyrek, Michał, Chocholska, Sylwia, Sompor, Jacek, Nogalski, Adam, Małecka-Massalska, Teresa, Hus, Marek
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963627/
https://ncbi.nlm.nih.gov/pubmed/29844872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25307
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