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Alternative RNA degradation pathways by the exonuclease Pop2p from Saccharomyces cerevisiae

The 3′ to 5′ exonuclease Pop2p (Caf1p) is part of the CCR4-NOT deadenylation complex that removes poly(A) tails from mRNAs in cells. Pop2p is structurally conserved in eukaryotes, but Saccharomyces cerevisiae Pop2p harbors noncanonical amino acids in its catalytic center. The enzymatic properties of...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Ye, Xuan, Axhemi, Armend, Jankowsky, Eckhard
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962489/
https://ncbi.nlm.nih.gov/pubmed/33408095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.078006.120
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