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Substrate selectivity by the exonuclease Rrp6p
The exoribonuclease Rrp6p is critical for RNA decay in the nucleus. While Rrp6p acts on a large range of diverse substrates, it does not indiscriminately degrade all RNAs. How Rrp6p accomplishes this task is not understood. Here, we measure Rrp6p–RNA binding and degradation kinetics in vitro at sing...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6969501/ https://ncbi.nlm.nih.gov/pubmed/31879344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913236117 |
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