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Structure of an Rrp6-RNA exosome complex bound to polyA RNA

The eukaryotic RNA exosome processes and degrades RNA by directing substrates to the distributive or processive 3′ to 5′ exoribonuclease activities of Rrp6 or Rrp44, respectively. The non-catalytic nine-subunit exosome core (Exo9) features a prominent central channel. While RNA can pass through the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nature
Hauptverfasser: Wasmuth, Elizabeth V., Januszyk, Kurt, Lima, Christopher D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310248/
https://ncbi.nlm.nih.gov/pubmed/25043052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13406
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