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Identification of m(6)A residues at single-nucleotide resolution using eCLIP and an accessible custom analysis pipeline

Methylation at the N(6) position of adenosine (m(6)A) is one of the most abundant RNA modifications found in eukaryotes; however, accurate detection of specific m(6)A nucleotides within transcripts has been historically challenging due to m(6)A and unmodified adenosine having virtually indistinguish...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Roberts, Justin T., Porman, Allison M., Johnson, Aaron M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962486/
https://ncbi.nlm.nih.gov/pubmed/33376190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.078543.120
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