A Cold Stress Inducible PERK/OGT Axis Controls TOM70-Assisted Mitochondrial Protein Import and Cristae Formation

The architecture of cristae provides a spatial mitochondrial organization that contains functional respiratory complexes. Several protein components including OPA1 and MICOS complex subunits organize cristae structure, but upstream regulatory mechanisms are largely unknown. Here, in vivo and in vitr...

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Publicat a:Cell Metab
Autors principals: Latorre-Muro, Pedro, O’Malley, Katherine E., Bennett, Christopher F., Perry, Elizabeth A., Balsa, Eduardo, Tavares, Clint D.J., Jedrychowski, Mark, Gygi, Steven M., Puigserver, Pere
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962155/
https://ncbi.nlm.nih.gov/pubmed/33592173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2021.01.013
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