Escin inhibits angiogenesis by suppressing interleukin-8 and vascular endothelial growth factor production by blocking nuclear factor-κB activation in pancreatic cancer cell lines

Pancreatic cancer (PaCa) is one of the most aggressive types of cancer. Thus, the development of new and more effective therapies is urgently required. Escin, a pentacyclic triterpenoid from the horse chestnut, has been reported to exhibit antitumor potential by reducing cell proliferation and block...

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Bibliografske podrobnosti
izdano v:Oncol Rep
Main Authors: Omi, Kan, Matsuo, Yoichi, Ueda, Goro, Aoyama, Yoshinaga, Kato, Tomokatsu, Hayashi, Yuichi, Imafuji, Hiroyuki, Saito, Kenta, Tsuboi, Ken, Morimoto, Mamoru, Ogawa, Ryo, Takahashi, Hiroki, Takiguchi, Shuji
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2021
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962110/
https://ncbi.nlm.nih.gov/pubmed/33760162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2021.8006
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