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Glycyrrhizin Attenuates Carcinogenesis by Inhibiting the Inflammatory Response in a Murine Model of Colorectal Cancer

Glycyrrhizin (GL), an important active ingredient of licorice root, which weakens the proinflammatory effects of high-mobility group box 1 (HMGB1) by blocking HMGB1 signaling. In this study, we investigated whether GL could suppress inflammation and carcinogenesis in an azoxymethane (AOM)/dextran so...

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Опубликовано в: :Int J Mol Sci
Главные авторы: Wang, Guifeng, Hiramoto, Keiichi, Ma, Ning, Yoshikawa, Nobuji, Ohnishi, Shiho, Murata, Mariko, Kawanishi, Shosuke
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961658/
https://ncbi.nlm.nih.gov/pubmed/33807620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052609
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