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Glycyrrhizin Attenuates Carcinogenesis by Inhibiting the Inflammatory Response in a Murine Model of Colorectal Cancer

Glycyrrhizin (GL), an important active ingredient of licorice root, which weakens the proinflammatory effects of high-mobility group box 1 (HMGB1) by blocking HMGB1 signaling. In this study, we investigated whether GL could suppress inflammation and carcinogenesis in an azoxymethane (AOM)/dextran so...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wang, Guifeng, Hiramoto, Keiichi, Ma, Ning, Yoshikawa, Nobuji, Ohnishi, Shiho, Murata, Mariko, Kawanishi, Shosuke
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961658/
https://ncbi.nlm.nih.gov/pubmed/33807620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052609
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