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Assessing G4-Binding Ligands In Vitro and in Cellulo Using Dimeric Carbocyanine Dye Displacement Assay

G-quadruplexes (G4) are the most actively studied non-canonical secondary structures formed by contiguous repeats of guanines in DNA or RNA strands. Small molecule mediated targeting of G-quadruplexes has emerged as an attractive tool for visualization and stabilization of these structures inside th...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Desai, Nakshi, Shah, Viraj, Datta, Bhaskar
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961521/
https://ncbi.nlm.nih.gov/pubmed/33807659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26051400
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