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Fluorine-19 Magnetic Resonance Imaging for Detection of Amyloid β Oligomers Using a Keto Form of Curcumin Derivative in a Mouse Model of Alzheimer’s Disease

Recent evidence suggests that the formation of soluble amyloid β (Aβ) aggregates with high toxicity, such as oligomers and protofibrils, is a key event that causes Alzheimer’s disease (AD). However, understanding the pathophysiological role of such soluble Aβ aggregates in the brain in vivo could be...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Yanagisawa, Daijiro, Ibrahim, Nor Faeizah, Taguchi, Hiroyasu, Morikawa, Shigehiro, Tomiyama, Takami, Tooyama, Ikuo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961357/
https://ncbi.nlm.nih.gov/pubmed/33806326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26051362
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