Rewiring of purine metabolism in response to acidosis stress in glioma stem cells

Glioma stem cells (GSCs) contribute to therapy resistance and poor outcomes for glioma patients. A significant feature of GSCs is their ability to grow in an acidic microenvironment. However, the mechanism underlying the rewiring of their metabolism in low pH remains elusive. Here, using metabolomic...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Xu, Xiaoyu, Wang, Liping, Zang, Qingce, Li, Shanshan, Li, Limei, Wang, Zhixing, He, Jiuming, Qiang, Boqin, Han, Wei, Zhang, Ruiping, Peng, Xiaozhong, Abliz, Zeper
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961141/
https://ncbi.nlm.nih.gov/pubmed/33723244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03543-9
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