Mass spectrometry imaging of phosphatidylcholine metabolism in lungs administered with therapeutic surfactants and isotopic tracers

Mass spectrometry imaging (MSI) visualizes molecular distributions throughout tissues but is blind to dynamic metabolic processes. Here, MSI with high mass resolution together with multiple stable isotope labeling provided spatial analyses of phosphatidylcholine (PC) metabolism in mouse lungs. Dysre...

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Dettagli Bibliografici
Pubblicato in:J Lipid Res
Autori principali: Ellis, Shane R., Hall, Emily, Panchal, Madhuriben, Flinders, Bryn, Madsen, Jens, Koster, Grielof, Heeren, Ron.M.A., Clark, Howard W., Postle, Anthony D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2021
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961103/
https://ncbi.nlm.nih.gov/pubmed/33453219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jlr.2021.100023
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