Prophylactic antigen‐specific T‐cells targeting seven viral and fungal pathogens after allogeneic haemopoietic stem cell transplant

OBJECTIVES: Adoptive immunotherapy using donor‐derived antigen‐specific T‐cells can prevent and treat infection after allogeneic haemopoietic stem cell transplant (HSCT). METHODS: We treated 11 patients with a prophylactic infusion of 2 × 10(7) cells per square metre donor‐derived T‐cells targeting...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Gottlieb, David Jonathan, Clancy, Leighton Edward, Withers, Barbara, McGuire, Helen Marie, Luciani, Fabio, Singh, Mandeep, Hughes, Brendan, Gloss, Brian, Kliman, David, Ma, Chun Kei Kris, Panicker, Shyam, Bishop, David, Dubosq, Ming‐Celine, Li, Ziduo, Avdic, Selmir, Micklethwaite, Kenneth, Blyth, Emily
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7960021/
https://ncbi.nlm.nih.gov/pubmed/33747509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1249
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