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A Potential Biomarker in Amyotrophic Lateral Sclerosis: Can Assessment of Brain Iron Deposition with SWI and Corticospinal Tract Degeneration with DTI Help?

BACKGROUND AND PURPOSE: Iron-mediated oxidative stress plays a pivotal role in the pathogenesis of amyotrophic lateral sclerosis. This study aimed to assess iron deposition qualitatively and quantitatively by using SWI and microstructural changes in the corticospinal tract by using DTI in patients w...

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Detalhes bibliográficos
Publicado no:AJNR Am J Neuroradiol
Main Authors: Sheelakumari, R., Madhusoodanan, M., Radhakrishnan, A., Ranjith, G., Thomas, B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Neuroradiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959949/
https://ncbi.nlm.nih.gov/pubmed/26494694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3174/ajnr.A4524
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