A Potential Biomarker in Amyotrophic Lateral Sclerosis: Can Assessment of Brain Iron Deposition with SWI and Corticospinal Tract Degeneration with DTI Help?

BACKGROUND AND PURPOSE: Iron-mediated oxidative stress plays a pivotal role in the pathogenesis of amyotrophic lateral sclerosis. This study aimed to assess iron deposition qualitatively and quantitatively by using SWI and microstructural changes in the corticospinal tract by using DTI in patients w...

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Bibliografiske detaljer
Udgivet i:AJNR Am J Neuroradiol
Main Authors: Sheelakumari, R., Madhusoodanan, M., Radhakrishnan, A., Ranjith, G., Thomas, B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Neuroradiology 2016
Fag:
Adult Brain
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959949/
https://ncbi.nlm.nih.gov/pubmed/26494694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3174/ajnr.A4524
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