Effect of TOP2A and ERCC1 gene polymorphisms on the efficacy and toxicity of cisplatin and etoposide-based chemotherapy in small cell lung cancer patients

INTRODUCTION: The main treatment regimen for small cell lung cancer (SCLC) involves platinum-based chemotherapy (cisplatin or carboplatin) and etoposide. Single nucleotide polymorphisms (SNPs) in TOP2A and ERCC1 genes were tested as prognostic and predictive factors in non-small cell lung cancer (NS...

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Detalhes bibliográficos
Publicado no:Arch Med Sci
Main Authors: Nicoś, Marcin, Rolska-Kopińska, Anna, Krawczyk, Paweł, Grenda, Anna, Bożyk, Aleksandra, Szczyrek, Michał, Milanowski, Janusz
Formato: Artigo
Idioma:Inglês
Publicado em: Termedia Publishing House 2020
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959040/
https://ncbi.nlm.nih.gov/pubmed/33747282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2020.92572
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