Promoter polymorphisms of TOP2A and ERCC1 genes as predictive factors for chemotherapy in non‐small cell lung cancer patients

BACKGROUND: Topoisomerase 2‐alpha (TOP2A) is an enzyme that controls topologic changes in DNA during transcription and replication. ERCC1 is an enzyme that takes part in DNA repair processes. The purpose of this study was to assess the predictive role of particular single nucleotide polymorphisms (S...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Grenda, Anna, Błach, Justyna, Szczyrek, Michał, Krawczyk, Paweł, Nicoś, Marcin, Kuźnar Kamińska, Barbara, Jakimiec, Monika, Balicka, Grażyna, Chmielewska, Izabela, Batura‐Gabryel, Halina, Sawicki, Marek, Milanowski, Janusz
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Clinical Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970032/
https://ncbi.nlm.nih.gov/pubmed/31797573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2743
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