Promoter polymorphisms of TOP2A and ERCC1 genes as predictive factors for chemotherapy in non‐small cell lung cancer patients

BACKGROUND: Topoisomerase 2‐alpha (TOP2A) is an enzyme that controls topologic changes in DNA during transcription and replication. ERCC1 is an enzyme that takes part in DNA repair processes. The purpose of this study was to assess the predictive role of particular single nucleotide polymorphisms (S...

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Vydáno v:Cancer Med
Hlavní autoři: Grenda, Anna, Błach, Justyna, Szczyrek, Michał, Krawczyk, Paweł, Nicoś, Marcin, Kuźnar Kamińska, Barbara, Jakimiec, Monika, Balicka, Grażyna, Chmielewska, Izabela, Batura‐Gabryel, Halina, Sawicki, Marek, Milanowski, Janusz
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Clinical Cancer Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970032/
https://ncbi.nlm.nih.gov/pubmed/31797573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2743
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