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A190 ATP-INDUCED INFLAMMASOME ACTIVATION GENERATES MITOCHONDRIAL ROS PRODUCTION IN MACROPHAGES

BACKGROUND: The etiology of Inflammatory Bowel Diseases is unknown; however, a dysfunctional immune response has been well characterized. The role of the NLRP3 inflammasome in IBD is controversial with both beneficial and detrimental results. This pathway is required for the secretion of the proinfl...

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Publicado en:J Can Assoc Gastroenterol
Autores principales: Bording-Jorgensen, M, Armstrong, H, Wine, E
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958832/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwab002.188
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