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A190 ATP-INDUCED INFLAMMASOME ACTIVATION GENERATES MITOCHONDRIAL ROS PRODUCTION IN MACROPHAGES

BACKGROUND: The etiology of Inflammatory Bowel Diseases is unknown; however, a dysfunctional immune response has been well characterized. The role of the NLRP3 inflammasome in IBD is controversial with both beneficial and detrimental results. This pathway is required for the secretion of the proinfl...

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Detalhes bibliográficos
Publicado no:J Can Assoc Gastroenterol
Main Authors: Bording-Jorgensen, M, Armstrong, H, Wine, E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958832/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwab002.188
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