Silencing CDCA8 Suppresses Hepatocellular Carcinoma Growth and Stemness via Restoration of ATF3 Tumor Suppressor and Inactivation of AKT/β–Catenin Signaling

SIMPLE SUMMARY: Although the overexpression of CDCA8 is frequently observed in hepatocellular carcinoma (HCC) tissues, the functions of CDCA8 during HCC development remain to be clarified. The aim of our study was to investigate if targeting CDCA8 could affect liver tumor phenotypes in vitro and in...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Jeon, Taewon, Ko, Min Ji, Seo, Yu-Ri, Jung, Soo-Jung, Seo, Daekwan, Park, So-Young, Park, Keon Uk, Kim, Kwang Seok, Kim, Mikyung, Seo, Ji Hae, Park, In-Chul, Kim, Min-Ji, Bae, Jae-Hoon, Song, Dae-Kyu, Cho, Chi Heum, Lee, Jae-Ho, Lee, Yun-Han
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958635/
https://ncbi.nlm.nih.gov/pubmed/33801424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13051055
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi