Senescence of Alveolar Type 2 Cells Drives Progressive Pulmonary Fibrosis

Rationale: Idiopathic pulmonary fibrosis (IPF) is an insidious and fatal interstitial lung disease associated with declining pulmonary function. Accelerated aging, loss of epithelial progenitor cell function and/or numbers, and cellular senescence are implicated in the pathogenies of IPF. Objectives...

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Détails bibliographiques
Publié dans:Am J Respir Crit Care Med
Auteurs principaux: Yao, Changfu, Guan, Xiangrong, Carraro, Gianni, Parimon, Tanyalak, Liu, Xue, Huang, Guanling, Mulay, Apoorva, Soukiasian, Harmik J., David, Gregory, Weigt, Stephen S., Belperio, John A., Chen, Peter, Jiang, Dianhua, Noble, Paul W., Stripp, Barry R.
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2021
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958503/
https://ncbi.nlm.nih.gov/pubmed/32991815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.202004-1274OC
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